Ze Wang, Professor, Hangzhou Normal University
王泽，教授，杭州师范大学
Title: Arterial Spin Labeling Perfusion MRI: from Bench to Bed
Abstract：
Arterial spin labeling perfusion (ASL) MRI is a noninvasive technique for quantifying cerebral blood flow (CBF) using radio-
magnetically labeled arterial blood as the endogenous tracer. Perfusion weighted signal is obtained from the difference between MR
images acquired with and without arterial spin labeling. Limited by the T1 decay of the labeled spins, labeling time in ASL is usually
limited. Because a post labeling delay time is required for transmitting spins to the imaging place, the available time for acquiring the
signal is also limited. Both these factors contribute a low signal-noise-ratio (SNR).Improving SNR is then a major aim of most ASL
technique development. Since the last decade, we have been working on advanced ASL imaging sequence and advanced ASL signal
processing algorithm. In this talk, I will introduce some of the work we performed in both directions. I will also show some of the
clinical applications based on ASL MRI.
Brief Bio:
Ze Wang, PhD, IEEE Senior Member, Professor and Principal Investigator of the Center for Cognition and Brain Disorder,
Hangzhou Normal University. Dr. Wang is currently supported by the Hangzhou Qianjiang Endowed Professorship.
Dr. Wang has published 65 peer-reviewed journal papers, 29 were first-authored, 20 were corresponding authored,
4 were sole-authored, and 10 were last authored. These papers have been cited more than 1300 times, resulting in an H-index of
24. Dr. Wang has developed 4 software packages: 3D Fast spin echo spiral readout ASL perfusion MRI sequence and online
reconstruction program, ASL signal processing toolbox(ASLtbx), Brain entropy mapping toolbox (BENtbx), multivariate-lesion
symptom mapping toolbox (SVR-LSM). All are freely available from https://cfn.upenn.edu/~zewang. Dr. Wang has been awarded
with the 2005 Excellent Thesis Award of Shanghai, and the Nomination Award of 2005 National 100 Excellent PhD Thesis. He
has been a board member or associate editors for several international journals, been ad hoc reviewer for more than 21 prestigious
journals and 2 top conferences.